BDBM50296668 3-(2-chloro-6-methylquinolin-3-yl)-1-phenylprop-2-en-1-one::CHEMBL559243
SMILES Cc1ccc2nc(Cl)c(\C=C\C(=O)c3ccccc3)cc2c1
InChI Key InChIKey=MFYDEDLDTMYCBI-CSKARUKUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50296668
Affinity DataKi: 9.18E+3nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merz Pharmaceuticals
Curated by ChEMBL
Merz Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat cortical membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Allosteric antagonist activity at mGluR1 in Sprague-Dawley rat cerebellar granule cells assessed as accumulation of [3H]inositol phosphate by liquid ...More data for this Ligand-Target Pair