BDBM50296674 (E)-1-Adamantan-1-yl-3-quinolin-3-yl-propenone::CHEMBL554700

SMILES O=C(\C=C\c1cnc2ccccc2c1)C12CC3CC(CC(C3)C1)C2

InChI Key InChIKey=IHMKNCCPYWKVEH-AATRIKPKSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296674   

TargetMetabotropic glutamate receptor 1(RAT)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296674((E)-1-Adamantan-1-yl-3-quinolin-3-yl-propenone | C...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296674((E)-1-Adamantan-1-yl-3-quinolin-3-yl-propenone | C...)
Affinity DataKi:  807nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat cortical membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed