BDBM50296691 3-(4-chlorophenyl)-1-(4-phenoxyphenyl)prop-2-en-1-one::CHEMBL558321

SMILES Clc1ccc(\C=C\C(=O)c2ccc(Oc3ccccc3)cc2)cc1

InChI Key InChIKey=MGTSFUGVJYPJBE-OVCLIPMQSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296691   

TargetMetabotropic glutamate receptor 1(RAT)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296691(3-(4-chlorophenyl)-1-(4-phenoxyphenyl)prop-2-en-1-...)
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296691(3-(4-chlorophenyl)-1-(4-phenoxyphenyl)prop-2-en-1-...)
Affinity DataIC50:  3.00E+4nMAssay Description:Allosteric antagonist activity at mGluR1 in Sprague-Dawley rat cerebellar granule cells assessed as accumulation of [3H]inositol phosphate by liquid ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed