BDBM50297891 3-(4-(3-(2,3-dimethylphenoxy)propoxy)phenyl)propanoic acid::CHEMBL561006

SMILES Cc1cccc(OCCCOc2ccc(CCC(O)=O)cc2)c1C

InChI Key InChIKey=KEYKHKKAFOXBBL-UHFFFAOYSA-N

Data  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50297891   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297891(3-(4-(3-(2,3-dimethylphenoxy)propoxy)phenyl)propan...)
Affinity DataEC50:  1.38E+4nMAssay Description:Agonist activity at human PPARalpha expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297891(3-(4-(3-(2,3-dimethylphenoxy)propoxy)phenyl)propan...)
Affinity DataEC50:  1.57E+4nMAssay Description:Agonist activity at human PPARgamma expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50297891(3-(4-(3-(2,3-dimethylphenoxy)propoxy)phenyl)propan...)
Affinity DataEC50:  1.12E+4nMAssay Description:Agonist activity at human PPARbeta expressed in african green monkey COS7 cells by Gal4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50297891(3-(4-(3-(2,3-dimethylphenoxy)propoxy)phenyl)propan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli BL21 assessed as enzyme product formation using arachidonic acid as subs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50297891(3-(4-(3-(2,3-dimethylphenoxy)propoxy)phenyl)propan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in A23187-stimulated human PMNL assessed as enzyme product formation preincubated 15 mins by RP-HPLC analysis in presenc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50297891(3-(4-(3-(2,3-dimethylphenoxy)propoxy)phenyl)propan...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 after 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed