BDBM50300104 CHEMBL582856::trans-1-cyclopentyl-6-(4-methyl-1-(pyridin-2-ylmethyl)pyrrolidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

SMILES C[C@@H]1CN(Cc2ccccn2)C[C@H]1c1nc2n(ncc2c(=O)[nH]1)C1CCCC1

InChI Key InChIKey=HXOYNKLVHFVKKC-RDTXWAMCSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50300104   

LigandPNGBDBM50300104(CHEMBL582856 | trans-1-cyclopentyl-6-(4-methyl-1-(...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant PDE1C expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50300104(CHEMBL582856 | trans-1-cyclopentyl-6-(4-methyl-1-(...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant PDE1C expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50300104(CHEMBL582856 | trans-1-cyclopentyl-6-(4-methyl-1-(...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50300104(CHEMBL582856 | trans-1-cyclopentyl-6-(4-methyl-1-(...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed