BDBM50300106 CHEMBL574449::trans-1-cyclopentyl-6-(4-methyl-1-((6-(trifluoromethyl)pyridin-3-yl)methyl)pyrrolidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one

SMILES C[C@@H]1CN(Cc2ccc(nc2)C(F)(F)F)C[C@H]1c1nc2n(ncc2c(=O)[nH]1)C1CCCC1

InChI Key InChIKey=VBTOPTREEDAWSQ-CXAGYDPISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300106   

LigandPNGBDBM50300106(CHEMBL574449 | trans-1-cyclopentyl-6-(4-methyl-1-(...)
Affinity DataIC50:  195nMAssay Description:Inhibition of human recombinant PDE1C expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50300106(CHEMBL574449 | trans-1-cyclopentyl-6-(4-methyl-1-(...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human recombinant PDE9A expressed in Sf9 cells by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed