BDBM50301112 (5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carbonyl)piperidin-3-yl pyrrolidine-1-carboxylate::CHEMBL586042

SMILES ONC(=O)[C@H]1CC(CN[C@@H]1C(=O)N1Cc2ccccc2C1)OC(=O)N1CCCC1

InChI Key InChIKey=QHTFXHUNNOAYME-BSOSBYQFSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50301112   

Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301112((5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carb...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50301112((5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carb...)
Affinity DataIC50:  186nMAssay Description:Inhibition of ADAM-10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301112((5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carb...)
Affinity DataIC50:  70nMAssay Description:Inhibition of HER-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301112((5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carb...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301112((5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carb...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301112((5S,6S)-5-(hydroxycarbamoyl)-6-(isoindoline-2-carb...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed