BDBM50301116 (3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phenylpiperazine-1-carbonyl)piperidin-3-yl 2,5-dihydro-1H-pyrrole-1-carboxylate::CHEMBL572091

SMILES CN1C[C@H](C[C@@H]([C@H]1C(=O)N1CCN(CC1)c1ccccc1)C(=O)NO)OC(=O)N1CC=CC1

InChI Key InChIKey=FQSNZGGDFVIKEV-UFYCRDLUSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50301116   

LigandPNGBDBM50301116((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50:  30nMAssay Description:Inhibition of ADAM-10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301116((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50:  581nMAssay Description:Inhibition of MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301116((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of HER-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301116((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301116((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of MMP-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50301116((3S,5S,6S)-5-(hydroxycarbamoyl)-1-methyl-6-(4-phen...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed