BDBM50305740 CHEMBL603858::N-(2-(indoline-1-carbonyl)phenyl)-N,4-dimethylbenzenesulfonamide

SMILES CN(c1ccccc1C(=O)N1CCc2ccccc12)S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=TUVRNXIVUMAXDC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50305740   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305740(N-(2-(indoline-1-carbonyl)phenyl)-N,4-dimethylbenz...)
Affinity DataIC50: 4.45E+4nMAssay Description:Displacement of [125I]human anaphylatoxin C5a from human C5a receptor expressed in CHO cells co-expressed with Galpha16 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305740(N-(2-(indoline-1-carbonyl)phenyl)-N,4-dimethylbenz...)
Affinity DataEC50: >6.00E+4nMAssay Description:Agonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as effect on anaphylatoxin C5a-induced intracellula...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50305740(N-(2-(indoline-1-carbonyl)phenyl)-N,4-dimethylbenz...)
Affinity DataIC50: 3.83E+4nMAssay Description:Antagonist activity at human C5a receptor expressed in CHO cells co-expressed with Galpha16 assessed as inhibition of anaphylatoxin C5a-induced intra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed