BDBM50307407 3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino}-carbonyl)-4-[(2-methylphenoxy)methyl]phenyl}propanoic acid::CHEMBL596745

SMILES CC(C)CC(NC(=O)c1cc(COc2ccccc2C)ccc1CCC(O)=O)c1cc(C)cc(C)c1

InChI Key InChIKey=PUQCPIMXFYPCIE-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50307407   

TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50307407(3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50307407(3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50307407(3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50307407(3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50307407(3-{2-({[1-(3,5-Dimethylphenyl)-3-methylbutyl]amino...)
Affinity DataIC50:  3.90nMAssay Description:Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase intracellular calcium level in prese...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed