BDBM50310653 (S)-3-chloro-2-fluoro-N-isobutyl-N-(pyrrolidin-3-yl)benzamide::CHEMBL1078073

SMILES CC(C)CN([C@H]1CCNC1)C(=O)c1cccc(Cl)c1F

InChI Key InChIKey=UWLXWGKTAMTBSF-NSHDSACASA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50310653   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310653((S)-3-chloro-2-fluoro-N-isobutyl-N-(pyrrolidin-3-y...)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]5HT from human 5HT transporter expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310653((S)-3-chloro-2-fluoro-N-isobutyl-N-(pyrrolidin-3-y...)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]noradrenaline from human NET receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310653((S)-3-chloro-2-fluoro-N-isobutyl-N-(pyrrolidin-3-y...)
Affinity DataKi:  2.56E+3nMAssay Description:Displacement of [3H]dopamine from human DAT receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50310653((S)-3-chloro-2-fluoro-N-isobutyl-N-(pyrrolidin-3-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed