BDBM50312917 2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl)thiazol-5-yloxy)acetic acid::CHEMBL1086856

SMILES OC(=O)COc1sc(nc1-c1cccc(F)c1)C(c1ccc(F)cc1)c1ccc(F)cc1

InChI Key InChIKey=DQFSKGLGNLOGRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312917   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312917(2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in HEK385-7 cells assessed as inhibition of PGD2-mediated beta-arrestin translocation preincuba...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50312917(2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl...)
Affinity DataIC50:  83nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK385-7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed