BDBM50316302 ((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-1-ium-9(6H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate::CHEMBL1094973
SMILES C[n+]1cn([C@@H]2O[C@H](COP([O-])(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12
InChI Key InChIKey=DKVRNHPCAOHRSI-KQYNXXCUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50316302
Affinity DataIC50: 5.72E+3nMAssay Description:Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA preincubated for 60 mins before mRNA addition by l...More data for this Ligand-Target Pair
Affinity DataIC50: 2.36E+3nMAssay Description:Inhibition of eIF4E-mediated translation in flexi rabbit reticulocyte lysate using luciferase mRNA treated simultaneously with mRNA by luminescence b...More data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Competitive inhibition of [3H]m7-GTP binding to human FLAG-His6 tagged eIF4E expressed in Escherichia coli by scintillation proximity assayMore data for this Ligand-Target Pair