BDBM50317905 3-[4-[(3-Cyanophenyl)amino]-2-({[(1R)-1-(3,5-dimethylphenyl)-3-methylbutyl]amino}carbonyl)phenyl]propanoic acid::CHEMBL1098047

SMILES CC(C)C[C@@H](NC(=O)c1cc(Nc2cccc(c2)C#N)ccc1CCC(O)=O)c1cc(C)cc(C)c1

InChI Key InChIKey=YRZUQVSDZQNFBE-MUUNZHRXSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50317905   

TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50317905(3-[4-[(3-Cyanophenyl)amino]-2-({[(1R)-1-(3,5-dimet...)
Affinity DataKi:  0.360nMAssay Description:Displacement of [3H]PGE2 from mouse EP3alpha receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50317905(3-[4-[(3-Cyanophenyl)amino]-2-({[(1R)-1-(3,5-dimet...)
Affinity DataKi:  220nMAssay Description:Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50317905(3-[4-[(3-Cyanophenyl)amino]-2-({[(1R)-1-(3,5-dimet...)
Affinity DataKi:  8.70E+3nMAssay Description:Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50317905(3-[4-[(3-Cyanophenyl)amino]-2-({[(1R)-1-(3,5-dimet...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50317905(3-[4-[(3-Cyanophenyl)amino]-2-({[(1R)-1-(3,5-dimet...)
Affinity DataIC50:  4.90nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed