BDBM50317907 3-[4-[(3-Chlorophenoxy)methyl]-2-({[(1R)-1-(3,5-dimethylphenyl)-3-methylbutyl]amino}carbonyl)phenyl]propanoicacid::CHEMBL1094156

SMILES CC(C)C[C@@H](NC(=O)c1cc(COc2cccc(Cl)c2)ccc1CCC(O)=O)c1cc(C)cc(C)c1

InChI Key InChIKey=VSONIJBYVAGXHF-MUUNZHRXSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50317907   

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50317907(3-[4-[(3-Chlorophenoxy)methyl]-2-({[(1R)-1-(3,5-di...)
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]PGE2 from mouse EP3alpha receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50317907(3-[4-[(3-Chlorophenoxy)methyl]-2-({[(1R)-1-(3,5-di...)
Affinity DataKi:  790nMAssay Description:Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50317907(3-[4-[(3-Chlorophenoxy)methyl]-2-({[(1R)-1-(3,5-di...)
Affinity DataKi:  4.40E+3nMAssay Description:Displacement of [3H]PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50317907(3-[4-[(3-Chlorophenoxy)methyl]-2-({[(1R)-1-(3,5-di...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50317907(3-[4-[(3-Chlorophenoxy)methyl]-2-({[(1R)-1-(3,5-di...)
Affinity DataIC50:  1.80nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed