BDBM50318159 8-Hydroxy-5-[(R)-1-hydroxy-2-(5,6-diethylindan-2-ylamino)-ethyl]-1H-quinolin-2-one::CHEMBL1095777::INDACATEROL
SMILES CCc1cc2CC(Cc2cc1CC)NC[C@H](O)c1ccc(O)c2[nH]c(=O)ccc12
InChI Key InChIKey=QZZUEBNBZAPZLX-QFIPXVFZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 29 hits for monomerid = 50318159
Affinity DataKi: 16nMAssay Description:Binding affinity to human beta2-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [125I]iodo-(+/-)-cyanopindolol from human adrenergic beta2 receptor expressed in CHO cells after 3 hrs by radio-ligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Displacement of [3H]CGP12177 from human beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Displacement of [3H]-dihydroalprenolol from human beta2-adrenoceptor expressed in HEK cells after 4 hrsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 76nMAssay Description:Displacement of [125I]cyanopindolol from human recombinant beta2 adrenergic receptor expressed in CHO cells by filtration assayMore data for this Ligand-Target Pair
Affinity DataKi: 91nMAssay Description:Displacement of [3H]CGP12177 from human beta-1 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataKi: 91nMAssay Description:Displacement of [125I]iodo-(+/-)-cyanopindolol from human adrenergic beta1 receptor expressed in CHO cells after 3 hrs by radio-ligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Binding affinity to human beta1-adrenoceptor by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.05E+3nMAssay Description:Displacement of [125I]7-HO-PIPAT from human D3R expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressing CHO-K1 cells incubated for 60 mins or 6 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 2.31E+3nMAssay Description:Agonist activity at beta1 adrenoreceptor in rat left atria assessed as induction of ionotropic effectMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at beta2 adrenoreceptor in guinea pig tracheal rings assessed as vasorelaxationMore data for this Ligand-Target Pair
Affinity DataEC50: 0.820nMAssay Description:Agonist activity at human beta2-adrenoceptor expressed in HEK cells assessed as increase of cAMP level after 10 mins by radioimmuno assayChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Binding affinity to beta1 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+4nMAssay Description:Binding affinity to dopamine 2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Binding affinity to adrenergic beta1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human dopamine D2 receptor expressed in CHO cells assessed as increase in GTPgamma35S binding by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.790nMAssay Description:Agonist activity at beta2 adrenoceptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Agonist activity at beta2 adrenergic receptor in guinea pig tracheal strip assessed as inhibition of electrically-induced bronchocontractile response...More data for this Ligand-Target Pair
Affinity DataEC50: 0.794nMAssay Description:Agonist activity at human beta2 adrenergic receptor expressed in HEK293 cells assessed as cAMP accumulation using [125I]cAMP by scintillation countin...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Agonist activity at adrenergic beta2 receptor in electrically-stimulated Dunkin-Hartley guinea pig tracheal strip assessed as inhibition of contracti...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Activity at human D2R expressed in CHO cells by radiolabelled [35S]GTPgammaS assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at adrenergic beta2 receptor in human A431 cells assessed as elevation of cAMP levelMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10nMAssay Description:Agonist activity at beta2-adrenoceptor in human bronchial smooth-muscle cell by cAMP assayMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at human beta2 adrenoceptor expressed in H292 cells assessed as increase in cAMP accumulation after 60 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at adrenergic beta1 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at human adrenergic beta2 receptor expressed in H292 cells assessed as stimulation of cAMP accumulation after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of SRSF6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Agonist activity at human beta2 adrenergic receptor assessed as increase in cAMP level by whole cell assayMore data for this Ligand-Target Pair