BDBM50319818 (+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl)piperazine::(-)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl)piperazine::1-(2-(2-(DIFLUOROMETHOXY)PHENYL)-1-PHENYLETHYL)PIPERAZINE (ENANTIOMERIC MIX)::1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl)piperazine::CHEMBL1083708

SMILES FC(F)Oc1ccccc1CC(N1CCNCC1)c1ccccc1

InChI Key InChIKey=VCVDPONUNCPTCQ-UHFFFAOYSA-N

Data  9 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50319818   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataKi:  6.56E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataKi:  6.56E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataKi:  6.56E+3nMAssay Description:Displacement of [3H]dopamine from human DAT expressed in HEK293 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataIC50:  1.27E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataIC50:  1.07E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataIC50:  1.07E+4nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50319818((+)-1-(2-(2-(difluoromethoxy)phenyl)-1-phenylethyl...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed