BDBM50321651 (4-(3-(1H-pyrazol-4-yl)imidazo[1,2-a]pyrazin-6-yl)phenyl)methanol::CHEMBL1170749
SMILES OCc1ccc(cc1)-c1cn2c(cnc2cn1)-c1cn[nH]c1
InChI Key InChIKey=ZGXOIUFSZFXEMV-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50321651
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of CHK1 by DELFIAMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.57E+7nMAssay Description:Inhibition of CHK1 (unknown origin) assessed as inhibition of CDC25 phosphorylation after 30 min by DELFIA assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of ABL1 by Z-lite assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
The Institute Of Cancer Research
Curated by ChEMBL
The Institute Of Cancer Research
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of CHK2 by DELFIA assayMore data for this Ligand-Target Pair