BDBM50323357 6-[(S)-1-(4-Chloro-phenyl)-ethyl]-4-cyclopropylmethyl-6,7-dihydro-5-thia-2,3a,6-triaza-indene 5,5-dioxide::CHEMBL1208801

SMILES C[C@H](N1Cc2cncn2C(CC2CC2)S1(=O)=O)c1ccc(Cl)cc1

InChI Key InChIKey=GIBBMQIFJKTBNZ-WHUIICBVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50323357   

TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50323357(6-[(S)-1-(4-Chloro-phenyl)-ethyl]-4-cyclopropylmet...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant CYP11B2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50323357(6-[(S)-1-(4-Chloro-phenyl)-ethyl]-4-cyclopropylmet...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human CYP3A4-mediated testosterone oxidationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50323357(6-[(S)-1-(4-Chloro-phenyl)-ethyl]-4-cyclopropylmet...)
Affinity DataIC50:  245nMAssay Description:Inhibition of human recombinant CYP11B1 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed