BDBM50325738 (R)-N-((6-chloro-4'-(trifluoromethyl)biphenyl-3-yl)methyl)-1-(3-methoxyphenyl)ethanamine::CHEMBL1224344

SMILES COc1cccc(c1)[C@@H](C)NCc1ccc(Cl)c(c1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=DYTWTDGDADYCBL-OAHLLOKOSA-N

Data  2 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50325738   

TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50325738((R)-N-((6-chloro-4'-(trifluoromethyl)biphenyl-3-yl...)
Show SMILES COc1cccc(c1)[C@@H](C)NCc1ccc(Cl)c(c1)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C23H21ClF3NO/c1-15(18-4-3-5-20(13-18)29-2)28-14-16-6-11-22(24)21(12-16)17-7-9-19(10-8-17)23(25,26)27/h3-13,15,28H,14H2,1-2H3/t15-/m1/s1
Affinity DataEC50: >5.00E+3nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in absence of extracellular calciumMore data for this Ligand-Target Pair
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50325738((R)-N-((6-chloro-4'-(trifluoromethyl)biphenyl-3-yl...)
Show SMILES COc1cccc(c1)[C@@H](C)NCc1ccc(Cl)c(c1)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C23H21ClF3NO/c1-15(18-4-3-5-20(13-18)29-2)28-14-16-6-11-22(24)21(12-16)17-7-9-19(10-8-17)23(25,26)27/h3-13,15,28H,14H2,1-2H3/t15-/m1/s1
Affinity DataEC50:  280nMAssay Description:Positive allosteric modulation of calcium sensing receptor by FLIPR assay in presence of extracellular calciumMore data for this Ligand-Target Pair