BDBM50327536 3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl)quinoline-7-carboxylic acid::CHEMBL1257381

SMILES OC(=O)c1ccc2cc(CNCCc3ccc(Br)cc3)c(nc2c1)-c1ccsc1

InChI Key InChIKey=KFUJPWYOARIOCE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327536   

TargetG-protein coupled bile acid receptor 1(Mus musculus)
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50327536(3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at mouse TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Kalypsys

Curated by ChEMBL
LigandPNGBDBM50327536(3-((4-bromophenethylamino)methyl)-2-(thiophen-3-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity at human TGR5 receptor expressed in HEK293 cells assessed as intracellular cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed