BDBM50327854 1-(1-(6-Chloronicotinoyl)piperidin-4-yl)-3-(4-(trifluoromethoxy)phenyl)urea::CHEMBL1257170::US9296693, 48

SMILES FC(F)(F)Oc1ccc(NC(=O)NC2CCN(CC2)C(=O)c2ccc(Cl)nc2)cc1

InChI Key InChIKey=PYAOQYAMUPHLJZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50327854   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
The Regents of The University of California

US Patent
LigandPNGBDBM50327854(1-(1-(6-Chloronicotinoyl)piperidin-4-yl)-3-(4-(tri...)
Affinity DataIC50:  0.600nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents of The University of California

US Patent
LigandPNGBDBM50327854(1-(1-(6-Chloronicotinoyl)piperidin-4-yl)-3-(4-(tri...)
Affinity DataIC50:  0.700nMpH: 7.0Assay Description:IC50 values were determined using a sensitive fluorescent based assay (Anal. Biochem. 2005, 343, 66-75). Cyano(2-methoxynaphthalen-6-yl)methyl trans-...More data for this Ligand-Target Pair
In DepthDetails US Patent