BDBM50328524 5,6-Dichloro-2-{(2S)-1-[2-methylalanyl-(betaS)-beta-methyl-L-phenylalanyl]pyrrolidin-2-yl}-1H-benzimidazole::CHEMBL1259207

SMILES C[C@H]([C@H](NC(=O)C(C)(C)N)C(=O)N1CCC[C@H]1c1nc2cc(Cl)c(Cl)cc2[nH]1)c1ccccc1

InChI Key InChIKey=BRJWVZQAVMCCBY-WVFSVQOHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50328524   

TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328524(5,6-Dichloro-2-{(2S)-1-[2-methylalanyl-(betaS)-bet...)
Affinity DataIC50:  60nMAssay Description:Inhibition of mouse PrCP by FRET in presence of 1% mouse serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328524(5,6-Dichloro-2-{(2S)-1-[2-methylalanyl-(betaS)-bet...)
Affinity DataIC50:  32nMAssay Description:Inhibition of mouse PrCP by FRETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328524(5,6-Dichloro-2-{(2S)-1-[2-methylalanyl-(betaS)-bet...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human PrCP by FRET in presence of 1% mouse serum albuminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal Pro-X carboxypeptidase(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328524(5,6-Dichloro-2-{(2S)-1-[2-methylalanyl-(betaS)-bet...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human PrCP by FRETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed