BDBM50329829 2-Chloro-5-{[2-(methylsulfanyl)-1H-benzimidazol-1-yl]acetyl}benzenesulfonamide::CHEMBL1271530::N-alkylated benzimidazole derivative, 4j

SMILES CSc1nc2ccccc2n1CC(=O)c1ccc(Cl)c(c1)S(N)(=O)=O

InChI Key InChIKey=YSDZWUSFFLGBDF-UHFFFAOYSA-N

Data  9 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50329829   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329829(2-Chloro-5-{[2-(methylsulfanyl)-1H-benzimidazol-1-...)
Affinity DataKd:  5.00E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329829(2-Chloro-5-{[2-(methylsulfanyl)-1H-benzimidazol-1-...)
Affinity DataKd:  1.00E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329829(2-Chloro-5-{[2-(methylsulfanyl)-1H-benzimidazol-1-...)
Affinity DataKd:  1.67E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329829(2-Chloro-5-{[2-(methylsulfanyl)-1H-benzimidazol-1-...)
Affinity DataKd:  1.43E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Institute Of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50329829(2-Chloro-5-{[2-(methylsulfanyl)-1H-benzimidazol-1-...)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 13 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329829(2-Chloro-5-{[2-(methylsulfanyl)-1H-benzimidazol-1-...)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 1 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329829(2-Chloro-5-{[2-(methylsulfanyl)-1H-benzimidazol-1-...)
Affinity DataKd:  1.00E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 2 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM50329829(2-Chloro-5-{[2-(methylsulfanyl)-1H-benzimidazol-1-...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 7 by thermal shift assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Institute Of Biotechnology

Curated by ChEMBL
LigandPNGBDBM50329829(2-Chloro-5-{[2-(methylsulfanyl)-1H-benzimidazol-1-...)
Affinity DataKd:  1.11E+3nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed