BDBM50329832 5-(1H-Benzimidazol-1-ylacetyl)-2-chlorobenzenesulfonamide::CHEMBL1272187::N-alkylated benzimidazole derivative, 4a::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 4
SMILES NS(=O)(=O)c1cc(ccc1Cl)C(=O)Cn1cnc2ccccc12
InChI Key InChIKey=XXDZSNJTAQNIAQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50329832
Affinity DataKd: 2.60nMAssay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as intrinsic thermodynamic equilibrium constant at p...More data for this Ligand-Target Pair
Affinity DataKon: 0.140M-1s-1Assay Description:Displacement of binding of [3H]-BRL 43694 to 5-hydroxytryptamine 3 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKon: 0.270M-1s-1Assay Description:Displacement of binding of [3H]-BRL 43694 to 5-hydroxytryptamine 3 receptor in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKd: 6.80nMAssay Description:Binding affinity to CA12 (unknown origin) assessed as intrinsic thermodynamic equilibrium constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.150M-1s-1Assay Description:Binding affinity to human full length His-tagged CA2 (1 to 260 residues) expressed in Escherichia coli BL21(DE3) assessed as dissociation rate consta...More data for this Ligand-Target Pair
Affinity DataKd: 13nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptors in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKon: 0.840M-1s-1Assay Description:Binding affinity to human CA9 catalytic domain expressed in mammalian expression system assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 4.90nMAssay Description:Binding affinity to human full length His-tagged CA2 (1 to 260 residues) expressed in Escherichia coli BL21(DE3) assessed as intrinsic thermodynamic ...More data for this Ligand-Target Pair