BDBM50329951 CHEMBL1271815::N-(3-(4-(2,3-dimethylphenyl)piperazin-1-yl)propyl)-6-isopropyl-2-methylpyrimidine-4-carboxamide Hydrochloride

SMILES CC(C)c1cc(nc(C)n1)C(=O)NCCCN1CCN(CC1)c1cccc(C)c1C

InChI Key InChIKey=ADGQMFGFECWRRY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50329951   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329951(CHEMBL1271815 | N-(3-(4-(2,3-dimethylphenyl)pipera...)
Affinity DataIC50:  1.21E+3nMAssay Description:Displacement of [3H]imipramine from human recombinant SERT receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329951(CHEMBL1271815 | N-(3-(4-(2,3-dimethylphenyl)pipera...)
Affinity DataIC50:  490nMAssay Description:Displacement of [3H]ketanserin from human recombinant 5HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Green Cross

Curated by ChEMBL
LigandPNGBDBM50329951(CHEMBL1271815 | N-(3-(4-(2,3-dimethylphenyl)pipera...)
Affinity DataIC50:  1.55E+3nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed