BDBM50331095 CHEMBL1289494::Tivozanib::US10464902, Tivozanib

SMILES COc1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)on4)c(Cl)c3)c2cc1OC

InChI Key InChIKey=SPMVMDHWKHCIDT-UHFFFAOYSA-N

Data  1 KI  20 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50331095   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50331095(CHEMBL1289494 | Tivozanib | US10464902, Tivozanib)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50331095(CHEMBL1289494 | Tivozanib | US10464902, Tivozanib)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
University Of Genoa

Curated by ChEMBL
LigandPNGBDBM50331095(CHEMBL1289494 | Tivozanib | US10464902, Tivozanib)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed