BDBM50334662 2-Methyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)-ethyl)pyrazolo[1,5-c]quinazoline::CHEMBL1642578
SMILES Cc1cc2c3ccccc3nc(CCc3nc(cn3C)-c3ccccc3)n2n1
InChI Key InChIKey=JTZGSTGVCPECEB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50334662
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
University of Sassari
Curated by ChEMBL
University of Sassari
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta countingMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
University of Sassari
Curated by ChEMBL
University of Sassari
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair