BDBM50334670 2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)pyrazolo[1,5-c]quinazoline::CHEMBL1642568

SMILES Cc1cc2c3cc(C)ccc3nc(CCc3nc(cn3C)-c3ccccc3)n2n1

InChI Key InChIKey=PXIUKGSKVQLIBW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50334670   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50334670(2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE5AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50334670(2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human PDE10A expressed in Sf9 cells using [3H]cAMP by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50334670(2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE1BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50334670(2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE3AMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50334670(2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE4D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50334670(2,9-Dimethyl-5-(2-(1-methyl-4-phenyl-1H-imidazol-2...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDE7BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed