BDBM50335379 CHEMBL1651532::N-(6-Methylpyridin-3-yl)-4-(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}benzylidene)piperidine-1-carboxamide

SMILES [#6]-c1ccc(-[#7]-[#6](=O)-[#7]-2-[#6]-[#6]\[#6](-[#6]-[#6]-2)=[#6]\c2cccc(-[#8]-c3ccc(cn3)C(F)(F)F)c2)cn1

InChI Key InChIKey=SCXPFFTVFSPORD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50335379   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335379(CHEMBL1651532 | N-(6-Methylpyridin-3-yl)-4-(3-{[5-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of CYP3A4 uisng testosterone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335379(CHEMBL1651532 | N-(6-Methylpyridin-3-yl)-4-(3-{[5-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50335379(CHEMBL1651532 | N-(6-Methylpyridin-3-yl)-4-(3-{[5-...)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of CYP3A4 uisng midazolam substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed