BDBM50337526 4-oxochroman-7-yl benzoate::CHEMBL1682821

SMILES O=C(Oc1ccc2C(=O)CCOc2c1)c1ccccc1

InChI Key InChIKey=NBOAWMUWUXJPTE-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50337526   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337526(4-oxochroman-7-yl benzoate | CHEMBL1682821)
Affinity DataEC50:  29.9nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50337526(4-oxochroman-7-yl benzoate | CHEMBL1682821)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu1 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50337526(4-oxochroman-7-yl benzoate | CHEMBL1682821)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu8 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337526(4-oxochroman-7-yl benzoate | CHEMBL1682821)
Affinity DataEC50:  128nMAssay Description:Positive allosteric modulation of human mGluR5a transfected in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50337526(4-oxochroman-7-yl benzoate | CHEMBL1682821)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed