BDBM50337526 4-oxochroman-7-yl benzoate::CHEMBL1682821
SMILES O=C(Oc1ccc2C(=O)CCOc2c1)c1ccccc1
InChI Key InChIKey=NBOAWMUWUXJPTE-UHFFFAOYSA-N
Data 5 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50337526
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 29.9nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu1 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu8 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Astrazeneca Pharmaceuticals
Curated by ChEMBL
Affinity DataEC50: 128nMAssay Description:Positive allosteric modulation of human mGluR5a transfected in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in HEK293 cells by fluorescent Ca2+ assayMore data for this Ligand-Target Pair