BDBM50343272 7-(4-(4-(3-chloro-2-(trifluoromethyl)phenyl)piperazin-1-yl)butoxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one::CHEMBL1774075

SMILES FC(F)(F)c1c(Cl)cccc1N1CCN(CCCCOc2ccc3CCC(=O)Nc3n2)CC1

InChI Key InChIKey=YFIBOKLKHXZNEU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343272   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343272(7-(4-(4-(3-chloro-2-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to human 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343272(7-(4-(4-(3-chloro-2-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2L receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343272(7-(4-(4-(3-chloro-2-(trifluoromethyl)phenyl)pipera...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed