BDBM50343630 Bis((-)-3-aminothiazolo-N-cyclopropylmethylmorphinan)sebacamide::CHEMBL1774951

SMILES O=C(CCCCCCCCC(=O)Nc1nc2cc3c(C[C@@H]4[C@@H]5CCCC[C@]35CCN4CC3CC3)cc2s1)Nc1nc2cc3c(C[C@@H]4[C@@H]5CCCC[C@]35CCN4CC3CC3)cc2s1

InChI Key InChIKey=GAWCJLWAXWTECZ-LGHBVLBESA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50343630   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343630(Bis((-)-3-aminothiazolo-N-cyclopropylmethylmorphin...)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]U69563 from human kappa-opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343630(Bis((-)-3-aminothiazolo-N-cyclopropylmethylmorphin...)
Affinity DataKi:  8.80nMAssay Description:Displacement of [3H]DAMGO from human mu-opioid receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343630(Bis((-)-3-aminothiazolo-N-cyclopropylmethylmorphin...)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]naltrindole from human delta-opioid receptor expressed in CHO cells after 3 hrs by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343630(Bis((-)-3-aminothiazolo-N-cyclopropylmethylmorphin...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human kappa-opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50343630(Bis((-)-3-aminothiazolo-N-cyclopropylmethylmorphin...)
Affinity DataEC50:  130nMAssay Description:Agonist activity at human mu-opioid receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding after 60 mins by scintillation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed