BDBM50343797 CHEMBL1774540::N-(3-Fluoro-4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-5-methoxy-1H-indole-2-carboxamide

SMILES COc1ccc2[nH]c(cc2c1)C(=O)NCCC(F)CN1CCN(CC1)c1ccccc1OC

InChI Key InChIKey=XUBVWPDKERMCAP-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50343797   

TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50343797(CHEMBL1774540 | N-(3-Fluoro-4-(4-(2-methoxyphenyl)...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [125I]-IABN from human dopamine D3 receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50343797(CHEMBL1774540 | N-(3-Fluoro-4-(4-(2-methoxyphenyl)...)
Affinity DataKi:  302nMAssay Description:Displacement of [125I]-IABN from human dopamine D2L receptor expressed in HEK293 cells after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50343797(CHEMBL1774540 | N-(3-Fluoro-4-(4-(2-methoxyphenyl)...)
Affinity DataKi:  1.17E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50343797(CHEMBL1774540 | N-(3-Fluoro-4-(4-(2-methoxyphenyl)...)
Affinity DataKi:  3.54E+3nMAssay Description:Displacement of [125I]DOI from 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50343797(CHEMBL1774540 | N-(3-Fluoro-4-(4-(2-methoxyphenyl)...)
Affinity DataIC50:  2.99E+3nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHO-K1 cells assessed as inhibition of dopamine-induced recruitment of beta-arrestin-2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50343797(CHEMBL1774540 | N-(3-Fluoro-4-(4-(2-methoxyphenyl)...)
Affinity DataIC50:  1.14E+3nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in CHOp cells assessed as inhibition of quinopirole-induced mitogenisisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed