BDBM50347496 CHEMBL1801579

SMILES Oc1cc(O)c(cc1Cl)-n1c2ccc(CNS(=O)(=O)c3ccc4ccccc4c3)cc2[nH]c1=O

InChI Key InChIKey=PFQZZOPIWVZUBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50347496   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347496(CHEMBL1801579)
Affinity DataIC50:  47nMAssay Description:Binding affinity to Hsp90alpha N-terminal ATPase domain by TR-FRET assay based competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50347496(CHEMBL1801579)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of Hsp90alpha ATPase activity by malachite green ATP-ase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed