BDBM50351425 CHEMBL1819478
SMILES CCCC\C(=C/c1cc(OCCc2ccc(cc2)C(F)(F)F)ccc1OCCc1ccc(cc1)C(F)(F)F)C(O)=O
InChI Key InChIKey=LKYYLGBNRZLTJP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50351425
TargetPeroxisome proliferator-activated receptor gamma(Human)
Goethe-University Frankfurt
Curated by ChEMBL
Goethe-University Frankfurt
Curated by ChEMBL
Affinity DataEC50: 7.20E+3nMAssay Description:Modulation of human PPARgamma-LBD expressed in african green monkey COS7 cells co-transfected with Gal4 assessed as activation of transactivation act...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Goethe University Frankfurt
Curated by ChEMBL
Zafes/Liff/Goethe University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 5-lipoxygenase-mediated product formation from arachidonic acid after 5 to 10 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of mPGES-1 in human IL-1beta-stimulated A549 cell microsomes assessed as reduction of PGE2 formation from PGH2 after 15 mins by RP-HPLC an...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Goethe University Frankfurt
Curated by ChEMBL
Zafes/Liff/Goethe University Frankfurt
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-lipoxygenase-mediated 5(S)-H(p)ETE formation in fMLP-stimulated human PMNL incubated 10 mins prior to fMLP challengeMore data for this Ligand-Target Pair