BDBM50354492 CHEMBL260994

SMILES Clc1ccc(cc1)N1CCN(CCCCC2C(=O)Nc3ccccc23)CC1

InChI Key InChIKey=JAOXKCOCADFHNG-UHFFFAOYSA-N

Data  11 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50354492   

Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354492(CHEMBL260994)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354492(CHEMBL260994)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]CT from human 5-HT7 receptor expressed in CHO cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354492(CHEMBL260994)
Affinity DataKi:  17.5nMAssay Description:Inhibition of 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354492(CHEMBL260994)
Affinity DataKi:  18nMAssay Description:Binding affinity to 5-HT2A receptor by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354492(CHEMBL260994)
Affinity DataKi:  42nMAssay Description:Inhibition of adrenergic alpha-1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354492(CHEMBL260994)
Affinity DataKi:  580nMAssay Description:Inhibition of 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354492(CHEMBL260994)
Affinity DataKi:  690nMAssay Description:Inhibition of 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354492(CHEMBL260994)
Affinity DataKi:  960nMAssay Description:Inhibition of dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354492(CHEMBL260994)
Affinity DataKi:  1.80E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in rat frontal cortex membrane after 45 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354492(CHEMBL260994)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of 5HT1A receptor in rat frontal cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Egis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50354492(CHEMBL260994)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed