BDBM50355057 CHEMBL1834751

SMILES Cc1nn(-c2ccc(cn2)C(=O)N[C@@H]2CCCc3cc(CN4CCCCC4)ccc23)c(=O)c2c(F)ccc(F)c12

InChI Key InChIKey=RNZVZOQUASDNJY-AREMUKBSSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355057   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50355057(CHEMBL1834751)
Affinity DataKi:  0.600nMAssay Description:Antagonist activity at human B1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Oryctolagus cuniculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50355057(CHEMBL1834751)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of rabbit B1 receptor by cellular calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50355057(CHEMBL1834751)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at human B1 receptor expressed in CHO cells by aequorin-based calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed