BDBM50358456 CHEMBL1614726

SMILES OCCOCCn1ccc2ncnc(Nc3cnc(Oc4cccc(c4)C(F)(F)F)c(Cl)c3)c12

InChI Key InChIKey=XPUIECRALWERTL-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358456   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50358456(CHEMBL1614726)
Affinity DataIC50:  11nMAssay Description:Inhibition of human N-terminus peptide (DYKDDDD)-tagged HER2 expressed in baculovirus infected insect cells using [gamma-32P]ATP as substrate after 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)