BDBM50359500 (R)Methamphetamine::CHEMBL1927030

SMILES CN[C@H](C)Cc1ccccc1

InChI Key InChIKey=MYWUZJCMWCOHBA-UHFFFAOYSA-N

Data  2 KI  10 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50359500   

TargetTrace amine-associated receptor 1(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359500BDBM50359500(CHEMBL1927030 | (R)Methamphetamine)
Affinity DataEC50:  1.19E+3nMAssay Description:Activation of rat TAAR1 expressed in HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359500BDBM50359500(CHEMBL1927030 | (R)Methamphetamine)
Affinity DataEC50:  2.44E+3nMAssay Description:Activation of mouse TAAR1 expressed in human HEK293 cells assessed as accumulation of [3H]cAMP after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rhesus macaque)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359500BDBM50359500(CHEMBL1927030 | (R)Methamphetamine)
Affinity DataEC50:  2.50E+3nMAssay Description:Activation of rhesus monkey TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein assessed as cAMP accumulation by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
Research Triangle Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50359500BDBM50359500(CHEMBL1927030 | (R)Methamphetamine)
Affinity DataEC50:  3.30E+3nMAssay Description:Activation of C-terminal HA epitope tagged human TAAR1 expressed in RD-HGA16 cells co-expressing Gq protein, Galpha16 by cAMP accumulation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed