BDBM50360231 CHEMBL1928185

SMILES Cc1cc(ccc1O)-c1ccc(nc1)C(=O)c1cccc(O)c1

InChI Key InChIKey=LQRVZFVKSBBPAZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50360231   

Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360231(CHEMBL1928185)
Affinity DataIC50:  5.48E+3nMAssay Description:Inhibition of human cytosolic 17beta-HSD1 in cell-free system using [2,4,6,7-3H]E1 as substrate after 10 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50360231(CHEMBL1928185)
Affinity DataIC50:  5.48E+3nMAssay Description:Inhibition of purified human placental cytosolic 17beta-HSD1 using [3H]-E1 substrate and NADH by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360231(CHEMBL1928185)
Affinity DataIC50:  260nMAssay Description:Inhibition of purified human placental microsomal 17beta-HSD2 using [3H]-E2 substrate and NAD+ by HPLC based radioactive displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50360231(CHEMBL1928185)
Affinity DataIC50:  260nMAssay Description:Inhibition of human microsomal 17beta-HSD2 in cell-free system using [2,4,6,7-3H]E2 as substrate after 20 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed