BDBM50361557 CHEMBL1089334

SMILES Nc1cccc(c1)S(=O)(=O)N1CCCN(CC1)S(=O)(=O)c1ccc2OCCOc2c1

InChI Key InChIKey=GMHIOMMKSMSRLY-UHFFFAOYSA-N

Data  3 EC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361557   

TargetPyruvate kinase PKM(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50361557(CHEMBL1089334)
Affinity DataEC50:  38nMAssay Description:Activation of human PKM2 assessed as ATP product formation after 1 hr by luminescent pyruvate kinase-luciferase coupled assayMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50361557(CHEMBL1089334)
Affinity DataEC50:  38nMAssay Description:Activation of PKM2 (unknown origin) Asp354, Phe26, Lys311 residuesMore data for this Ligand-Target Pair
TargetPyruvate kinase PKM(Homo sapiens (Human))
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50361557(CHEMBL1089334)
Affinity DataEC50:  38nMAssay Description:Activation of human recombinant full length His-tagged PKM2 (Asp354, Lys311, Glu397, Gly315 residues)More data for this Ligand-Target Pair