BDBM50364679 CHEMBL1951468::US8785634, 2

SMILES [O-][n+]1ccc(Cl)cc1C1OC2(CCN(Cc3ccc(OC(F)(F)F)cc3)CC2)c2ccccc12

InChI Key InChIKey=ZZLWRNKWIAOSML-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50364679   

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364679(CHEMBL1951468 | US8785634, 2)
Affinity DataIC50: 1.30nMAssay Description:The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2014
Entry Details
Go to US Patent

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50364679(CHEMBL1951468 | US8785634, 2)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human PrCPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50364679(CHEMBL1951468 | US8785634, 2)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of mouse PrCPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed