BDBM50365128 CHEMBL1949835::CHEMBL2216906
SMILES CN1CC(C)(COc2ccc(cc2)C(N)=N)Oc2ccc(cc12)N(CC(O)=O)Cc1cc(F)cc(F)c1
InChI Key InChIKey=JJCBUVHDWHZUID-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50365128
Affinity DataKi: 760nMAssay Description:Inhibition of thrombin using S-2238 as substrate preincubated for 15 mins prior substrate addition measured for every 10 secs by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataKi: 9.80E+3nMAssay Description:Inhibition of factor 10a using S-2222 as substrate preincubated for 15 mins prior substrate addition measured for every 10 secs by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of biotinylated fibrinogen from human alpha2b-beta3 receptor after 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of human recombinant VEGFR2 expressed in Sf9 insect cells assessed as inhibition of poly(Glu,Tyr) 4:1 substrate phosphorylation by radiome...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Displacement of biotinylated fibrinogen from human alpha5-beta3 receptor after 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair