BDBM50366356 ASIMADOLINE HYDROCHLORIDE::EMD-61753

SMILES CN([C@H](CN1CC[C@H](O)C1)c1ccccc1)C(=O)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=JHLHNYVMZCADTC-UHFFFAOYSA-N

Data  4 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50366356   

TargetKappa-type opioid receptor(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50366356(EMD-61753 | ASIMADOLINE HYDROCHLORIDE)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human kappa opioid receptor expressed in COS7 cells after 60 mins IP1 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50366356(EMD-61753 | ASIMADOLINE HYDROCHLORIDE)
Affinity DataKi:  2nMAssay Description:Affinity at K opioid receptor on membranes prepared from guinea pig cerebellum by [3H]- 69593 displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetKappa-type opioid receptor(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50366356(EMD-61753 | ASIMADOLINE HYDROCHLORIDE)
Affinity DataKi:  5.60nMAssay Description:Binding affinity to human recombinant KOR assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed