BDBM50366495 (+)butaclamol::CHEMBL1255588
SMILES CC(C)(C)[C@@]1(O)CCN2C[C@@H]3c4ccccc4CCc4cccc([C@H]2C1)c34
InChI Key InChIKey=ZZJYIKPMDIWRSN-TZBSWOFLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 30 hits for monomerid = 50366495
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]- spiperone radioligand binding at the dopamine binding site of rat caudateMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Binding affinity was tested on Dopamine receptor D2 using radioligand [3H]spiroperidolMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]spiperone from human D2 receptor transfected in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat straitum tissue after 20 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]methyl-spiperone from human dopamine D2s receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Potency was measured by the displacement of [3H]spiperone binding to human D2 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.740nMAssay Description:Binding affinity to human dopamine D2S receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.851nMAssay Description:Inhibitory constant against binding of [125I]- IBZM to rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Competitive binding assay against Dopamine receptor D2 in rat striatal membranes and [125I]-IBF radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Binding affinity against Dopamine receptor D1 rat striatal receptor using [3H]SCH-23390More data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]ketanserin hydrochloride from 5-HT2A receptor (unknown origin) expressed in HEK293 cell membranes incubated for 15 mins by liquid...More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Binding affinity against Dopamine receptor D2 rat striatal membranes using [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 3.61nMAssay Description:Inhibitory constant against dopamine D2 receptor using 0.2 nM [3H]-spiperoneMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293 cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Non-selective inhibitory activity was determined against 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 185nMAssay Description:Potency was measured by the displacement of [3H]-spiperone binding to human D4 dopaminergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 5.20E+3nMAssay Description:Displacement of [3H]- QNB binding at the muscarinic-cholinergic binding site of rat brain S1More data for this Ligand-Target Pair
Affinity DataIC50: 0nMAssay Description:Antagonist required to inhibit Dopamine receptor D2 photoinactivation by 50% with Iodazidoclebopride using [3H]spiperoneMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human dopamine D3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human dopamine D2 receptorMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University Of North Carolina
Curated by ChEMBL
University Of North Carolina
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]spiroperidolMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:The IC50 value was reported as apparent, since [3H]NCA was purported to be irreversible. Result indicates the mean of two separate experiments, each ...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]spiroperidol binding to rat striatal membrane using 0.5 nM ligand.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Concentration inhibiting the specific binding of [3H]spiroperidol by 50%More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Binding affinity to human dopamine D2S receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Binding affinity to human dopamine D2S receptor by radioligand displacement assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair