BDBM50370517 CHEMBL4163428::US10954217, Example 00227
SMILES CN1CCN(CC1)c1ccc2CN(Cc2c1)C(=O)OCc1ccccc1
InChI Key InChIKey=UETLZTFBKJSNHG-UHFFFAOYSA-N
Data 18 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50370517
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
TargetSigma non-opioid intracellular receptor 1(Cavia porcellus (Guinea pig))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 250nMAssay Description:Displacement of [3H]-Pentazocine from sigma1 receptor in guinea pig brain membrane by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 254nMAssay Description:Displacement of [3H]-Rauwolscine from human adrenergic alpha2C receptor expressed in stable MDCK cells after 90 mins by microbeta scintillation count...More data for this Ligand-Target Pair
Affinity DataKi: 285nMAssay Description:Displacement of [125I]-iodoaminopotentidine from human histamine H2 receptor expressed in stable HEK cells after 90 mins by microbeta scintillation c...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 302nMAssay Description:Displacement of [3H]-Mesulergine from human 5-HT2C receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1E(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 403nMAssay Description:Displacement of [3H]-5-HT from human 5-HT1E receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 454nMAssay Description:Displacement of [3H]-Rauwolscine from human adrenergic alpha2B receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting met...More data for this Ligand-Target Pair
Affinity DataKi: 476nMAssay Description:Displacement of [3H]-alpha-methylhistamine from human histamine H3 receptor expressed in HEK Flp-In cells after 90 mins by microbeta scintillation co...More data for this Ligand-Target Pair
Affinity DataKi: 483nMAssay Description:Displacement of [3H]-Pyrilamine from human histamine H1 receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting meth...More data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 487nMAssay Description:Displacement of [3H]-Rauwolscine from human adrenergic alpha2A receptor expressed in stable MDCK cells after 90 mins by microbeta scintillation count...More data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Rattus norvegicus (Rat))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 553nMAssay Description:Displacement of [3H]-ditolylguanidine from sigma2 receptor in rat PC12 cells by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSigma intracellular receptor 2(Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 1.02E+3nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 1.12E+3nMAssay Description:Displacement of [3H]-LSD from human 5-HT2B receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 1.38E+3nMAssay Description:Displacement of [3H]-Citalopram from human SERT receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 1.43E+3nMAssay Description:Displacement of [3H]-5-CT from human 5-HT1B receptor expressed in stable HEK cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Displacement of [3H]-SCH23390 from human dopamine D1 receptor expressed in HEKT cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
University Of Texas At Austin
Curated by ChEMBL
University Of Texas At Austin
Curated by ChEMBL
Affinity DataKi: 2.61E+3nMAssay Description:Displacement of [3H]-WAY100635 from human 5-HT1A receptor expressed in stable CHO cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair