BDBM50370548 NOGALAMYCIN

SMILES CO[C@H]1[C@H](C)O[C@@H](O[C@H]2C[C@](C)(O)[C@H](C(=O)OC)c3cc4C(=O)c5c6O[C@@H]7O[C@@](C)([C@H](O)[C@H]([C@@H]7O)N(C)C)c6cc(O)c5C(=O)c4c(O)c23)[C@H](OC)[C@]1(C)OC

InChI Key InChIKey=KGTDRFCXGRULNK-JYOBTZKQSA-N

Data  3 IC50

PDB links: 8 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50370548   

TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre For Genetic Engineering And Biotechnology

LigandPNGBDBM50370548(NOGALAMYCIN)
Affinity DataIC50:  3.30E+3nMpH: 8.0 T: 2°CAssay Description:The hydrolysis of ATP catalyzed by PfUDN was assayed by measuring the formation of Pi from [γ-32P] ATP. The reaction mixture of 10 μl conta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus)
University Of Wollongong

Curated by ChEMBL
LigandPNGBDBM50370548(NOGALAMYCIN)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against hepatitis C virus helicaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre For Genetic Engineering And Biotechnology

LigandPNGBDBM50370548(NOGALAMYCIN)
Affinity DataIC50:  3.50E+3nMpH: 8.0 T: 2°CAssay Description:Helicase assay was demonstrated using the purified fraction of PfUDN. The specially designed partial duplex substrate consisted of a 32P-labelled 47-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed