BDBM50370595 OXYCODONE::Oxycontin::US1184575, oxycodone::US9233167, Oxycodone

SMILES COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O

InChI Key InChIKey=BRUQQQPBMZOVGD-XFKAJCMBSA-N

Data  19 KI  3 IC50  10 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50370595   

TargetKappa-type opioid receptor(Guinea pig)
Biological Research Centre of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  325nMAssay Description:Displacement of [3H]HS-665 from KOR in guinea pig brain membranes after 60 mins by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rat)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi:  2.66E+3nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Guinea pig)
Biological Research Centre of The Hungarian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]U69593 from kappa opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mouse)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataEC50:  1.60E+4nMAssay Description:Agonist activity at mouse KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
University of Texas At Austin

Curated by ChEMBL
LigandPNGBDBM50370595(OXYCODONE | Oxycontin | US1184575, oxycodone | US9...)
Affinity DataEC50:  1.60E+4nMAssay Description:Agonist activity at human KOR assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by cell based TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank