BDBM50375319 PREGNENOLONE

SMILES CC(=O)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI Key InChIKey=ORNBQBCIOKFOEO-QGVNFLHTSA-N

Data  1 KI  2 IC50  1 Kd

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50375319   

TargetCorticosteroid-binding globulin(Homo sapiens)
Nippon Zoki Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50375319(PREGNENOLONE)
Affinity DataKi:  5.89E+3nMAssay Description:Binding affinity to human CBG receptor (corticosteroid-binding globulins)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50375319(PREGNENOLONE)
Affinity DataIC50:  8.14E+4nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50375319(PREGNENOLONE)
Affinity DataKd:  71nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Homo sapiens (Human))
Act

Curated by ChEMBL
LigandPNGBDBM50375319(PREGNENOLONE)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed